منابع مشابه
Nitrofurantoin Induced Liver Injury
Drug induced liver injury is a recognised cause of acute liver failure. A wide range of drugs have been implicated, of which the most common are Paracetamol and antibiotics. Nitrofurantoin is a commonly prescribed antimicrobial which may cause liver injury from either acute or chronic exposure. This complication was thought to occur with an extremely low incidence; however recent data suggests ...
متن کاملFatal nitrofurantoin lung.
Nitrofurantoin is a drug commonly used for urinary tract infections. It acts by damaging bacterial DNA. It is given in dose of 50-100 mg orally and is generally considered a safe drug but has occasionally been known to cause pulmonary toxicity which is usually reversible and only rarely fatal. We present a case of an elderly lady receiving nitrofurantoin for her urinary tract infection who deve...
متن کاملNitrofurantoin-induced lung- and hepatotoxicity.
We present the case of a patient referred to the gastroenterology service for investigation of abnormal liver function tests. She had been taking nitrofurantoin for 16 months as prophylaxis against urinary tract infections. CT scan showed evidence of lung pneumonitis and low attenuation in the liver parenchyma. Nitrofurantoin-induced pneumonitis and hepatotoxicity was diagnosed. The patient res...
متن کاملLung toxicity and Nitrofurantoin: the tip of the iceberg?
A 56-year-old female was referred to the respiratory clinic by her general practitioner with a 3-month history of dyspnoea and cough. She was a non-smoker. Her cough persisted despite several trials of medication, including antibiotics and inhaled bronchodilator and steroid therapy. Her past medical history included cervical cancer in 1997 with vault relapse in 1999, treated by hysterectomy, ch...
متن کاملPleural effusion: An uncommon manifestation of nitrofurantoin-induced pulmonary injury
Nitrofurantoin has been documented as a cause of acute, sub-acute, and chronic pulmonary injury. This is a case of an 82 year-old female who presented with multiple episodes of respiratory symptoms due to recurrent pleural effusions after beginning nitrofurantoin therapy for urinary tract infection prophylaxis. Due to the rarity of pleural effusion as an adverse reaction to nitrofurantoin, the ...
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ژورنال
عنوان ژورنال: Age and Ageing
سال: 2004
ISSN: 0002-0729,1468-2834
DOI: 10.1093/ageing/afh131